Molecular mechanism of the recognition of bacterially cleaved immunoglobulin by the immune regulatory receptor LILRA2

Human leukocyte immunoglobulin-like receptors (LILRs) typically regulate immune activation by binding to the human leukocyte antigen class I molecules. LILRA2, a member of the LILR family, was recently reported to bind to other unique ligands, the bacterially degraded Igs (N-truncated Igs), for the...

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Udgivet i:J Biol Chem
Main Authors: Yamazaki, Rika, Furukawa, Atsushi, Hirayasu, Kouyuki, Yumoto, Kohei, Fukuhara, Hideo, Arase, Hisashi, Maenaka, Katsumi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363141/
https://ncbi.nlm.nih.gov/pubmed/32424043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013354
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