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The unfoldase ClpC1 of Mycobacterium tuberculosis regulates the expression of a distinct subset of proteins having intrinsically disordered termini

The human pathogen Mycobacterium tuberculosis (Mtb) harbors a well-orchestrated Clp (caseinolytic protease) proteolytic machinery consisting of two oligomeric segments, a barrel-shaped heterotetradecameric protease core comprising the ClpP1 and ClpP2 subunits, and hexameric ring-like ATP-dependent u...

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Pubblicato in:J Biol Chem
Autori principali: Lunge, Ajitesh, Gupta, Radhika, Choudhary, Eira, Agarwal, Nisheeth
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363115/
https://ncbi.nlm.nih.gov/pubmed/32409584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013456
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