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MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation
Mitochondrial function is critically dependent on the folding of the mitochondrial inner membrane into cristae; indeed, numerous human diseases are associated with aberrant crista morphologies. With the MICOS complex, OPA1 and the F(1)F(o)‐ATP synthase, key players of cristae biogenesis have been id...
Gespeichert in:
| Veröffentlicht in: | EMBO J |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7361284/ https://ncbi.nlm.nih.gov/pubmed/32567732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019104105 |
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