Mesenchymal stromal/stem cells modulate response to experimental sepsis-induced lung injury via regulation of miR-27a-5p in recipient mice

INTRODUCTION: Mesenchymal stromal cell (MSC) therapy mitigates lung injury and improves survival in murine models of sepsis. Precise mechanisms of therapeutic benefit remain poorly understood. OBJECTIVES: To identify host-derived regulatory elements that may contribute to the therapeutic effects of...

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Bibliographic Details
Published in:Thorax
Main Authors: Younes, Nadim, Zhou, Louis, Amatullah, Hajera, Mei, Shirley H J, Herrero, Raquel, Lorente, Jose Angel, Stewart, Duncan J, Marsden, Philip, Liles, W Conrad, Hu, Pingzhao, dos Santos, Claudia C
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2020
Subjects:
Critical Care
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7361025/
https://ncbi.nlm.nih.gov/pubmed/32546573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2019-213561
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