Serum neuronal exosomes predict and differentiate Parkinson’s disease from atypical parkinsonism

OBJECTIVE: Parkinson’s disease is characterised neuropathologically by α-synuclein aggregation. Currently, there is no blood test to predict the underlying pathology or distinguish Parkinson’s from atypical parkinsonian syndromes. We assessed the clinical utility of serum neuronal exosomes as biomar...

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Gepubliceerd in:J Neurol Neurosurg Psychiatry
Hoofdauteurs: Jiang, Cheng, Hopfner, Franziska, Katsikoudi, Antigoni, Hein, Robert, Catli, Candan, Evetts, Samuel, Huang, Yongzhi, Wang, Hong, Ryder, John W, Kuhlenbaeumer, Gregor, Deuschl, Guenther, Padovani, Alessandro, Berg, Daniela, Borroni, Barbara, Hu, Michele T, Davis, Jason J, Tofaris, George K
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMJ Publishing Group 2020
Onderwerpen:
Neurodegeneration
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7361010/
https://ncbi.nlm.nih.gov/pubmed/32273329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2019-322588
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