Long Noncoding RNA PVT1 Promotes Prostate Cancer Metastasis by Increasing NOP2 Expression via Targeting Tumor Suppressor MicroRNAs

BACKGROUND: Metastatic disease caused by prostate cancer (PCa) is the principal cause of PCa-related mortality. Long non-protein-coding RNAs may possess significant cellular functions. Plasmacytoma variant translocation 1 (PVT1), a long non-coding RNA encoded by the human PVT1 gene, is an oncogene,...

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Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Sun, Feng, Wu, Ke, Yao, Zhixian, Mu, Xingyu, Zheng, Zhong, Sun, Menghao, Wang, Yong, Liu, Zhihong, Zhu, Yiyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7360424/
https://ncbi.nlm.nih.gov/pubmed/32764963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S242441
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