Nano-Encapsulation of Coenzyme Q10 in Secondary and Tertiary Nano-Emulsions for Enhanced Cardioprotection and Hepatoprotection in Human Cardiomyocytes and Hepatocytes During Exposure to Anthracyclines and Trastuzumab

INTRODUCTION: CoenzymeQ(10) (CoQ(10)) is a well-known antioxidant and anti-inflammatory agent with cardioprotective properties. However, clinical trials based on its oral administration have failed to provide significant effect on cardiac functionality. The main limitation of CoQ(10) is based on its...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Quagliariello, Vincenzo, Vecchione, Raffaele, De Capua, Alberta, Lagreca, Elena, Iaffaioli, Rosario Vincenzo, Botti, Gerardo, Netti, Paolo A, Maurea, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359894/
https://ncbi.nlm.nih.gov/pubmed/32764923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S245170
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