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Immune Sensing Mechanisms that Discriminate Self from Altered Self and Foreign Nucleic Acids

All lifeforms have developed highly sophisticated systems equipped to detect altered self and non-self nucleic acids (NA). In vertebrates, NA-sensing receptors safeguard the integrity of the organism by detecting pathogens, dyshomeostasis and damage, and inducing appropriate responses to eliminate p...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Bartok, Eva, Hartmann, Gunther
Formato: Artigo
Idioma:Inglês
Publicado em: Published by Elsevier Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359798/
https://ncbi.nlm.nih.gov/pubmed/32668228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.06.014
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