Generation of blastocyst-like structures from mouse embryonic and adult cell cultures

A single mouse blastomere from until 8-cell embryo can generate an entire blastocyst. Whether laboratory cultured cells retain a similar generative capacity remains unknown. Starting from a single stem cell type, extended pluripotent stem (EPS) cells, we established a 3D differentiation system that...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Li, Ronghui, Zhong, Cuiqing, Yu, Yang, Liu, Haisong, Sakurai, Masahiro, Yu, Leqian, Min, Zheying, Shi, Lei, Wei, Yulei, Takahashi, Yuta, Liao, Hsin-Kai, Qiao, Jie, Deng, Hongkui, Delicado, Estrella Nuñez, Esteban, Concepcion Rodriguez, Wu, Jun, Belmonte, Juan Carlos Izpisua
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359735/
https://ncbi.nlm.nih.gov/pubmed/31626770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.09.029
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