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Defective migration and dysmorphology of neutrophil granulocytes in atypical chronic myeloid leukemia treated with ruxolitinib

BACKGROUND: The identification of pathologically altered neutrophil granulocyte migration patterns bears strong potential for surveillance and prognostic scoring of diseases. We recently identified a strong correlation between impaired neutrophil motility and the disease stage of myelodysplastic syn...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Bornemann, Lea, Schuster, Marc, Schmitz, Saskia, Sobczak, Charlyn, Bessen, Clara, Merz, Simon F., Jöckel, Karl-Heinz, Haverkamp, Thomas, Gunzer, Matthias, Göthert, Joachim R.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359613/
https://ncbi.nlm.nih.gov/pubmed/32660441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07130-7
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