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Radix Sophorae Flavescentis induces apoptosis through by Caspase, MAPK Activation and ROS Signaling Pathways in 5637 Human Bladder Cancer Cells

The anti-cancer mechanisms of Radix Sophorae Flavescentis were investigated in 5637 bladder cancer cells. Radix Sophorae Flavescentis extract (RSF) (50‑400 µg/ml) inhibited the proliferation of 5637 cells and increased sub‑G1 phase ratios. RSF‑induced cell death was associated with the down-regulati...

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Detalhes bibliográficos
Publicado no:Int J Med Sci
Main Authors: Jo, Geoncheol, Kwon, Min Ji, Kim, Jeong Nam, Kim, Byung Joo
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359395/
https://ncbi.nlm.nih.gov/pubmed/32669949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.45831
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