Catalytic inhibition of H3K9me2 writers disturbs epigenetic marks during bovine nuclear reprogramming

Orchestrated events, including extensive changes in epigenetic marks, allow a somatic nucleus to become totipotent after transfer into an oocyte, a process termed nuclear reprogramming. Recently, several strategies have been applied in order to improve reprogramming efficiency, mainly focused on rem...

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Publicado en:Sci Rep
Autores principales: Sampaio, Rafael Vilar, Sangalli, Juliano Rodrigues, De Bem, Tiago Henrique Camara, Ambrizi, Dewison Ricardo, del Collado, Maite, Bridi, Alessandra, de Ávila, Ana Clara Faquineli Cavalcante Mendes, Macabelli, Carolina Habermann, de Jesus Oliveira, Lilian, da Silveira, Juliano Coelho, Chiaratti, Marcos Roberto, Perecin, Felipe, Bressan, Fabiana Fernandes, Smith, Lawrence Charles, Ross, Pablo J, Meirelles, Flávio Vieira
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359371/
https://ncbi.nlm.nih.gov/pubmed/32661262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67733-9
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