Suppressing DRP1-mediated mitochondrial fission and mitophagy increases mitochondrial apoptosis of hepatocellular carcinoma cells in the setting of hypoxia

Transarterial embolization/transarterial chemoembolization (TAE/TACE) is the acceptable palliative treatment for hepatocellular carcinoma (HCC), mainly through ischemic necrosis induced by arterial embolization. However, how HCC cells survive under such ischemic hypoxic condition remains unclear, wh...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Lin, Xia-Hui, Qiu, Bai-Quan, Ma, Min, Zhang, Rui, Hsu, Shu-Jung, Liu, Hua-Hua, Chen, Jun, Gao, Dong-Mei, Cui, Jie-Feng, Ren, Zheng-Gang, Chen, Rong-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359348/
https://ncbi.nlm.nih.gov/pubmed/32661251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00251-5
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