Rechallenge of denosumab in jaw osteonecrosis of patients with unresectable giant cell tumour of bone: a case series analysis and literature review

OBJECTIVES: Giant cell tumour of bone (GCTB) is a rare tumour, generally managed with surgery. Treatment of the very rare unresectable advanced/metastatic GCTB is challenging and denosumab is the only current available medical option, an anti-RANKL monoclonal antibody inhibiting osteolysis. An uncom...

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Bibliografiske detaljer
Udgivet i:ESMO Open
Main Authors: Raimondi, Alessandra, Simeone, Noemi, Guzzo, Marco, Maniezzo, Massimo, Collini, Paola, Morosi, Carlo, Greco, Francesca Gabriella, Frezza, Anna Maria, Casali, Paolo G, Stacchiotti, Silvia
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2020
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Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359187/
https://ncbi.nlm.nih.gov/pubmed/32661185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/esmoopen-2019-000663
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