Correlates of clinical benefit from immunotherapy and targeted therapy in metastatic renal cell carcinoma: comprehensive genomic and transcriptomic analysis

BACKGROUND: The clinical significance of tumor-specific genomic alterations in metastatic renal cell carcinoma (mRCC) is emerging, with several studies suggesting an association between PBRM1 mutations and response with immunotherapy (IO). We sought to determine genomic predictors of differential re...

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書目詳細資料
發表在:J Immunother Cancer
Main Authors: Dizman, Nazli, Lyou, Yung, Salgia, Nicholas, Bergerot, Paulo Gustavo, Hsu, JoAnn, Enriquez, Daniel, Izatt, Tyler, Trent, Jeffrey M, Byron, Sara, Pal, Sumanta
格式: Artigo
語言:Inglês
出版: BMJ Publishing Group 2020
主題:
Immunotherapy Biomarkers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359179/
https://ncbi.nlm.nih.gov/pubmed/32661119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000953
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