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Longitudinal biomarkers in amyotrophic lateral sclerosis

OBJECTIVE: To investigate neurodegenerative and inflammatory biomarkers in people with amyotrophic lateral sclerosis (PALS), evaluate their predictive value for ALS progression rates, and assess their utility as pharmacodynamic biomarkers for monitoring treatment effects. METHODS: De‐identified, lon...

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Vydáno v:Ann Clin Transl Neurol
Hlavní autoři: Huang, Fen, Zhu, Yuda, Hsiao‐Nakamoto, Jennifer, Tang, Xinyan, Dugas, Jason C., Moscovitch‐Lopatin, Miriam, Glass, Jonathan D., Brown, Robert H., Ladha, Shafeeq S., Lacomis, David, Harris, Jeffrey M., Scearce‐Levie, Kimberly, Ho, Carole, Bowser, Robert, Berry, James D.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359115/
https://ncbi.nlm.nih.gov/pubmed/32515902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.51078
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