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IGF-1C hydrogel improves the therapeutic effects of MSCs on colitis in mice through PGE(2)-mediated M2 macrophage polarization

Background: Mesenchymal stem cell (MSC)-based therapies hold great promise for the treatment of inflammatory bowel disease (IBD). In order to optimize and maximize the therapeutic benefits of MSCs, we investigated whether cotransplantation of a chitosan (CS)-based injectable hydrogel with immobilize...

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Bibliografske podrobnosti
izdano v:Theranostics
Main Authors: Cao, Xiaocang, Duan, Liyun, Hou, Huixing, Liu, Yue, Chen, Shang, Zhang, Shuaiqiang, Liu, Yuanyuan, Wang, Chen, Qi, Xin, Liu, Na, Han, Zhibo, Zhang, Dekui, Han, Zhong-Chao, Guo, Zhikun, Zhao, Qiang, Li, Zongjin
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7359093/
https://ncbi.nlm.nih.gov/pubmed/32685014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.45434
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