Detection of somatic TP53 mutation in surgically resected small-cell lung cancer by targeted exome sequencing: association with longer relapse-free survival

OBJECTIVES: Few reports have explored clinical biomarkers, including those identified by targeted exome sequencing (TES) of surgically resected small-cell lung cancer (SCLC) and correlation with patient survival. PATIENTS AND METHODS: We collected formalin-fixed paraffin-embedded tumor samples from...

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Publicado no:Heliyon
Main Authors: Yokouchi, Hiroshi, Nishihara, Hiroshi, Harada, Toshiyuki, Yamazaki, Shigeo, Kikuchi, Hajime, Oizumi, Satoshi, Uramoto, Hidetaka, Tanaka, Fumihiro, Harada, Masao, Akie, Kenji, Sugaya, Fumiko, Fujita, Yuka, Takamura, Kei, Kojima, Tetsuya, Higuchi, Mitsunori, Honjo, Osamu, Minami, Yoshinori, Watanabe, Naomi, Nishimura, Masaharu, Suzuki, Hiroyuki, Dosaka-Akita, Hirotoshi, Isobe, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7358392/
https://ncbi.nlm.nih.gov/pubmed/32685741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e04439
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