Expression and Purification of ZASP Subdomains and Clinically Important Isoforms: High-Affinity Binding to G-Actin

Z-disc-associated, alternatively spliced, PDZ motif-containing protein (ZASP) is a principal component of the sarcomere. The three prevalent isoforms of ZASP in skeletal muscle are generated by alternative splicing of exons 9 and 10. The long isoforms, either having (ZASP-L) or lacking exon 10 (ZASP...

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Bibliographic Details
Published in:Biochemistry
Main Authors: Watts, Norman R., Zhuang, Xiaolei, Kaufman, Joshua D., Palmer, Ira W., Dearborn, Altaira D., Coscia, Stephen, Blech-Hermoni, Yotam, Alfano, Caterina, Pastore, Annalisa, Mankodi, Ami, Wingfield, Paul T.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7357845/
https://ncbi.nlm.nih.gov/pubmed/28349680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00067
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