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SIRT3 promotes auditory function in young adult FVB/nJ mice but is dispensable for hearing recovery after noise exposure

Noise-induced hearing loss (NIHL) affects millions of people worldwide and presents a large social and personal burden. Pharmacological activation of SIRT3, a regulator of the mitochondrial oxidative stress response, has a protective effect on hearing thresholds after traumatic noise damage in mice....

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Patel, Sally, Shah, Lisa, Dang, Natalie, Tan, Xiaodong, Almudevar, Anthony, White, Patricia M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7357743/
https://ncbi.nlm.nih.gov/pubmed/32658908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235491
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