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An Optimized Chromatin Immunoprecipitation Protocol for Quantification of Protein-DNA Interactions

Transcription factors are important regulators of cell fate and function. Knowledge about where transcription factors are bound in the genome is crucial for understanding their function. A common method to study protein-DNA interactions is chromatin immunoprecipitation (ChIP). Here, we present a rev...

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Bibliografiske detaljer
Udgivet i:STAR Protoc
Main Authors: de Jonge, Wim J., Brok, Mariël, Kemmeren, Patrick, Holstege, Frank C.P.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7357673/
https://ncbi.nlm.nih.gov/pubmed/32685929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2020.100020
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