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Phase I Trial of Fenretinide Lym-X-Sorb Oral Powder in Adults with Solid Tumors and Lymphomas
BACKGROUND: The synthetic retinoid fenretinide (N-(4- hydroxyphenyl)retinamide, 4-HPR) has shown promising anticaiicer activity in preclinical studies, but its limited oral bioavailability has hindered clinical assessment. A novel lipid matrix, Lym-X-Sorb (LXS), was evaluated to improve fenretinide...
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| Publicado no: | Anticancer Res |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7357208/ https://ncbi.nlm.nih.gov/pubmed/21498721 |
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