Integrin α6 mediates the drug resistance of acute lymphoblastic B-cell leukemia

Resistance to multimodal chemotherapy continues to limit the prognosis of acute lymphoblastic leukemia (ALL). This occurs in part through a process called adhesion-mediated drug resistance, which depends on ALL cell adhesion to the stroma through adhesion molecules, including integrins. Integrin α6...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Gang, Eun Ji, Kim, Hye Na, Hsieh, Yao-Te, Ruan, Yongsheng, Ogana, Heather A., Lee, Solomon, Pham, Jennifer, Geng, Huimin, Park, Eugene, Klemm, Lars, Willman, Cheryl L., Carroll, William L., Mittelman, Steven D., Orgel, Etan, Oberley, Matthew J., Parekh, Chintan, Abdel-Azim, Hisham, Bhojwani, Deepa, Wayne, Alan S., De Arcangelis, Adèle, Georges-Labouesse, Elisabeth, Wayner, Elizabeth, Bonig, Halvard, Minasyan, Aspram, ten Hoeve, Johanna, Graeber, Thomas G., Müschen, Markus, Heisterkamp, Nora, Kim, Yong-Mi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2020
Soggetti:
Lymphoid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7357190/
https://ncbi.nlm.nih.gov/pubmed/32219444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019001417
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