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Differential Anti-Proliferative and Anti-Migratory Activities of Ursolic Acid, 3-O-Acetylursolic Acid and Their Combination Treatments with Quercetin on Melanoma Cells

We evaluate how 3-acetylation modulates the in vitro activity of ursolic acid in melanoma cells alone or in combination treatments with quercetin. Anti-proliferative studies on A375 cells and adult human dermal fibroblasts included analyses on cell cycle distribution, caspase activity, phosphatidyls...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biomolecules
Hauptverfasser: AlQathama, Aljawharah, Shao, Luying, Bader, Ammar, Khondkar, Proma, Gibbons, Simon, M Prieto, Jose
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356947/
https://ncbi.nlm.nih.gov/pubmed/32545262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10060894
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