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Molecular Image-Based Prediction Models of Nuclear Receptor Agonists and Antagonists Using the DeepSnap-Deep Learning Approach with the Tox21 10K Library

The interaction of nuclear receptors (NRs) with chemical compounds can cause dysregulation of endocrine signaling pathways, leading to adverse health outcomes due to the disruption of natural hormones. Thus, identifying possible ligands of NRs is a crucial task for understanding the adverse outcome...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Matsuzaka, Yasunari, Uesawa, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356846/
https://ncbi.nlm.nih.gov/pubmed/32549344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25122764
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