Human Mesenchymal Stem Cells Overexpressing Interleukin 2 Can Suppress Proliferation of Neuroblastoma Cells in Co-Culture and Activate Mononuclear Cells In Vitro

High-dose recombinant interleukin 2 (IL2) therapy has been shown to be successful in renal cell carcinoma and metastatic melanoma. However, systemic administration of high doses of IL2 can be toxic, causing capillary leakage syndrome and stimulating pro-tumor immune response. One of the strategies t...

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Publicado en:Bioengineering (Basel)
Autores principales: Chulpanova, Daria S., Solovyeva, Valeriya V., James, Victoria, Arkhipova, Svetlana S., Gomzikova, Marina O., Garanina, Ekaterina E., Akhmetzyanova, Elvira R., Tazetdinova, Leysan G., Khaiboullina, Svetlana F., Rizvanov, Albert A.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356660/
https://ncbi.nlm.nih.gov/pubmed/32560387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering7020059
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