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Design, Synthesis, and Preliminary Immunological Studies of MUC1-Based Antitumor Vaccines Adjuvanted with R- and S-FSL-1

[Image: see text] Fibroblast stimulating lipopeptide 1 (FSL-1) is the ligand of TLR2 and TLR6 and can be used as the vaccine adjuvant to prepare antitumor vaccines. However, FSL-1 is a stereoisomeric mixture that contains the R stereoisomer and S stereoisomer, and it is still unclear which stereoiso...

詳細記述

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書誌詳細
出版年:ACS Med Chem Lett
主要な著者: Liu, Yonghui, Yan, Bocheng, Wang, Zhaoyu, Zhu, Haomiao, Yin, Xiaona, Wang, Kun, Wang, Menglei, Zhao, Wei
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2020
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356377/
https://ncbi.nlm.nih.gov/pubmed/32676142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00579
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