Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment after spinal cord injury in rodents

Following a spinal cord injury, axons fail to regenerate in the adult mammalian central nervous system, leading to permanent deficits in sensory and motor functions. Increasing neuronal activity after an injury using electrical stimulation or rehabilitation can enhance neuronal plasticity and result...

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Udgivet i:Sci Transl Med
Main Authors: Hutson, Thomas H., Kathe, Claudia, Palmisano, Ilaria, Bartholdi, Kay, Hervera, Arnau, Virgiliis, Francesco De, McLachlan, Eilidh, Zhou, Luming, Kong, Guiping, Barraud, Quentin, Danzi, Matt C., Medrano-Fernandez, Alejandro, Lopez-Atalaya, Jose P., Boutillier, Anne L., Sinha, Sarmistha H., Singh, Akash K., Chaturbedy, Piyush, Moon, Lawrence D. F., Kundu, Tapas K., Bixby, John L., Lemmon, Vance P., Barco, Angel, Courtine, Gregoire, Giovanni, Simone Di
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355732/
https://ncbi.nlm.nih.gov/pubmed/30971452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaw2064
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