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Supersaturated Lipid-Based Formulations to Enhance the Oral Bioavailability of Venetoclax

Increasing numbers of beyond Rule-of-Five drugs are emerging from discovery pipelines, generating a need for bio-enabling formulation approaches, such as lipid-based formulations (LBF), to ensure maximal in vivo exposure. However, many drug candidates display insufficient lipid solubility, leading t...

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Bibliografiske detaljer
Udgivet i:Pharmaceutics
Main Authors: Koehl, Niklas J., Henze, Laura J., Kuentz, Martin, Holm, René, Griffin, Brendan T.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355533/
https://ncbi.nlm.nih.gov/pubmed/32570753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12060564
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