Chrysophanol Prevents Lipopolysaccharide-Induced Hepatic Stellate Cell Activation by Upregulating Apoptosis, Oxidative Stress, and the Unfolded Protein Response

Hepatic stellate cell (HSC) activation is a vital driver of liver fibrosis. Recent research efforts have emphasized the clearance of activated HSCs by apoptosis, senescence, or reversion to the quiescent state. LPS induces human HSC activation directly and contributes to liver disease progression. C...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Wu, Jiunn-Sheng, Chiu, Valeria, Lan, Chou-Chin, Wang, Ming-Chieh, Tzeng, I.-Shiang, Kuo, Chan-Yen, Hsieh, Po-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355365/
https://ncbi.nlm.nih.gov/pubmed/32714424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/8426051
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