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Hopper: a mathematically optimal algorithm for sketching biological data

MOTIVATION: Single-cell RNA-sequencing has grown massively in scale since its inception, presenting substantial analytic and computational challenges. Even simple downstream analyses, such as dimensionality reduction and clustering, require days of runtime and hundreds of gigabytes of memory for tod...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: DeMeo, Benjamin, Berger, Bonnie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355272/
https://ncbi.nlm.nih.gov/pubmed/32657375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa408
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