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Human Cerebrospinal Fluid Promotes Neuronal Circuit Maturation of Human Induced Pluripotent Stem Cell-Derived 3D Neural Aggregates

Human induced pluripotent stem cell (hiPSC)-derived in vitro neural and organoid models resemble fetal, rather than adult brain properties, indicating that currently applied cultivation media and supplements are insufficient to achieve neural maturation beyond the fetal stage. In vivo, cerebrospinal...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Stem Cell Reports
Päätekijät: Izsak, Julia, Seth, Henrik, Theiss, Stephan, Hanse, Eric, Illes, Sebastian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355159/
https://ncbi.nlm.nih.gov/pubmed/32521247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.05.006
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