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Phenoxodiol sensitizes metastatic colorectal cancer cells to 5-fluorouracil- and oxaliplatin-induced apoptosis through intrinsic pathway

Colorectal cancer (CRC) is one of the most common types of cancer seen in the world. 5-Fluorouracil (5-Fu) plus Oxaliplatin (1-OHP) remains the backbone of CRC chemotherapeutics, but with limited success. Phenoxodiol (Pxd) is an isoflavone analog with antitumor activity against various types of canc...

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Detalhes bibliográficos
Publicado no:EXCLI J
Main Authors: Yaylaci, Esra, Onen, Hacer Ilke, Yar Saglam, Atiye Seda
Formato: Artigo
Idioma:Inglês
Publicado em: Leibniz Research Centre for Working Environment and Human Factors 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355152/
https://ncbi.nlm.nih.gov/pubmed/32665777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2020-2042
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