Up-regulated cytotrophoblast DOCK4 contributes to over-invasion in placenta accreta spectrum

In humans, a subset of placental cytotrophoblasts (CTBs) invades the uterus and its vasculature, anchoring the pregnancy and ensuring adequate blood flow to the fetus. Appropriate depth is critical. Shallow invasion increases the risk of pregnancy complications, e.g., severe preeclampsia. Overly dee...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: McNally, Leah, Zhou, Yan, Robinson, Joshua F., Zhao, Guangfeng, Chen, Lee-may, Chen, Hao, Kim, M. Yvonne, Kapidzic, Mirhan, Gormley, Matthew, Hannibal, Roberta, Fisher, Susan J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355036/
https://ncbi.nlm.nih.gov/pubmed/32576693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1920776117
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