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A role for NPY-NPY2R signaling in albuminuric kidney disease

Albuminuria is an independent risk factor for the progression to end-stage kidney failure, cardiovascular morbidity, and premature death. As such, discovering signaling pathways that modulate albuminuria is desirable. Here, we studied the transcriptomes of podocytes, key cells in the prevention of a...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Lay, Abigail C., Barrington, A. Fern, Hurcombe, Jenny A., Ramnath, Raina D., Graham, Mark, Lewis, Philip A., Wilson, Marieangela C., Heesom, Kate J., Butler, Matthew J., Perrett, Rebecca M., Neal, Chris R., Herbert, Eleanor, Mountjoy, Edward, Atan, Denize, Nair, Viji, Ju, Wenjun, Nelson, Robert G., Kretzler, Matthias, Satchell, Simon C., McArdle, Craig A., Welsh, Gavin I., Coward, Richard J. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7355002/
https://ncbi.nlm.nih.gov/pubmed/32561647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004651117
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