Hedgehog–FGF signaling axis patterns anterior mesoderm during gastrulation

The mechanisms used by embryos to pattern tissues across their axes has fascinated developmental biologists since the founding of embryology. Here, using single-cell technology, we interrogate complex patterning defects and define a Hedgehog (Hh)–fibroblast growth factor (FGF) signaling axis require...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Guzzetta, Alexander, Koska, Mervenaz, Rowton, Megan, Sullivan, Kaelan R., Jacobs-Li, Jessica, Kweon, Junghun, Hidalgo, Hunter, Eckart, Heather, Hoffmann, Andrew D., Back, Rebecca, Lozano, Stephanie, Moon, Anne M., Basu, Anindita, Bressan, Michael, Pott, Sebastian, Moskowitz, Ivan P.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2020
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354932/
https://ncbi.nlm.nih.gov/pubmed/32561646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1914167117
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