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Higher anhedonia during withdrawal from initial opioid exposure is protective against subsequent opioid self-administration in rats.

RATIONALE. Understanding factors contributing to individual differences in vulnerability to opioid addiction is essential for developing more effective preventions and treatments, yet few reliable behavioral predictors of subsequent opioid self-administration have been identified in rodents. Sensiti...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Swain, Yayi, Muelken, Peter, Skansberg, Annika, Lanzdorf, Danielle, Haave, Zachary, LeSage, Mark G., Gewirtz, Jonathan C., Harris, Andrew C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354901/
https://ncbi.nlm.nih.gov/pubmed/32388620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-020-05532-w
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