Peroxisome Proliferator-Activated Receptor Gamma Agonist Attenuates Liver Fibrosis by Several Fibrogenic Pathways in an Animal Model of Cholestatic Fibrosis

PURPOSE: Peroxisome proliferator-activated receptor gamma (PPAR-γ) has a key role in hepatic fibrogenesis by virtue of its effect on the hepatic stellate cells (HSCs). Although many studies have shown that PPAR-γ agonists inhibit liver fibrosis, the mechanism remains largely unclear, especially rega...

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Detalhes bibliográficos
Publicado no:Pediatr Gastroenterol Hepatol Nutr
Main Authors: Alatas, Fatima Safira, Matsuura, Toshiharu, Pudjiadi, Antonius Hocky, Wijaya, Stephanie, Taguchi, Tomoaki
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354870/
https://ncbi.nlm.nih.gov/pubmed/32704495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5223/pghn.2020.23.4.346
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