Sam68 mediates leptin signaling and action in human granulosa cells: possible role in leptin resistance in PCOS

INTRODUCTION: Polycystic ovary syndrome (PCOS) is a complex metabolic disorder associated with ovulatory dysfunction, hyperandrogenism, obesity, and insulin resistance, that leads to subfertility. Sam68 is an RNA-binding protein with signaling functions that is ubiquitously expressed, including gona...

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Bibliografische gegevens
Gepubliceerd in:Endocr Connect
Hoofdauteurs: Vilariño-García, Teresa, Pérez-Pérez, Antonio, Santamaría-López, Esther, Prados, Nicolás, Fernández-Sánchez, Manuel, Sánchez-Margalet, Víctor
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Bioscientifica Ltd 2020
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354740/
https://ncbi.nlm.nih.gov/pubmed/32375121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-20-0062
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