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A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins

Pain thresholds are, in part, set as a function of emotional and internal states by descending modulation of nociceptive transmission in the spinal cord. Neurons of the rostral ventromedial medulla (RVM) are thought to critically contribute to this process; however, the neural circuits and synaptic...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: François, Amaury, Low, Sarah A., Sypek, Elizabeth I., Christensen, Amelia J., Sotoudeh, Chaudy, Beier, Kevin T., Ramakrishnan, Charu, Ritola, Kimberly D., Sharif-Naeini, Reza, Deisseroth, Karl, Delp, Scott L., Malenka, Robert C., Luo, Liqun, Hantman, Adam W., Scherrer, Grégory
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354674/
https://ncbi.nlm.nih.gov/pubmed/28162807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.01.008
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