OnabotulinumtoxinA Displays Greater Biological Activity Compared to IncobotulinumtoxinA, Demonstrating Non-Interchangeability in Both In Vitro and In Vivo Assays

Differences in botulinum neurotoxin manufacturing, formulation, and potency evaluation can impact dose and biological activity, which ultimately affect duration of action. The potency of different labeled vials of incobotulinumtoxinA (Xeomin(®); 50 U, 100 U, or 200 U vials; incobotA) versus onabotul...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Rupp, David, Nicholson, Greg, Canty, David, Wang, Joanne, Rhéaume, Catherine, Le, Linh, Steward, Lance E., Washburn, Mark, Jacky, Birgitte P., Broide, Ron S., Philipp-Dormston, Wolfgang G., Brin, Mitchell F., Brideau-Andersen, Amy
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354455/
https://ncbi.nlm.nih.gov/pubmed/32545832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12060393
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