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Dibutyltin alters immune cell production of the pro-inflammatory cytokines interleukin (IL) 1β and IL-6: role of mitogen-activated protein kinases and changes in mRNA

Dibutyltin (DBT) is used to stabilize plastics and as a deworming agent in some poultry. It is found in human blood (levels as high as 0.3 μM). Interleukin (IL) 1 beta (IL-1β) and IL-6 are pro-inflammatory cytokines produced by lymphocytes, monocytes, and other cells. Elevated levels of IL-1β and IL...

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Podrobná bibliografie
Vydáno v:J Appl Toxicol
Hlavní autoři: Sushak, Linda, Gabure, Sahra, Maise, JaQuel, Arnett, Jessica, Whalen, Margaret M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354221/
https://ncbi.nlm.nih.gov/pubmed/32141102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jat.3964
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