Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic Pathogen Klebsiella oxytoca

Tilimycin is an enterotoxin produced by the opportunistic pathogen Klebsiella oxytoca that causes antibiotic-associated hemorrhagic colitis (AAHC). This pyrrolobenzodiazepine (PBD) natural product is synthesized by a bimodular nonribosomal peptide synthetase (NRPS) pathway comprised of three protein...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Alexander, Evan M., Kreitler, Dale F., Guidolin, Valeria, Hurben, Alexander K., Drake, Eric, Villalta, Peter W., Balbo, Silvia, Gulick, Andrew M., Aldrich, Courtney C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354218/
https://ncbi.nlm.nih.gov/pubmed/32485104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00326
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados