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Successful treatment of refractory hyperferritinemic syndromes with canakinumab: a report of two cases

BACKGROUND: Hyperferritinemic syndromes are systemic inflammatory disorders characterized by a dysfunctional immune response, which leads to excessive activation of the monocyte-macrophage system with hypercytokinemia and may pursue a rapidly fatal course. CASE PRESENTATION: We describe two patients...

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Publicado en:Pediatr Rheumatol Online J
Autores principales: Papa, Riccardo, Natoli, Valentina, Caorsi, Roberta, Minoia, Francesca, Gattorno, Marco, Ravelli, Angelo
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353681/
https://ncbi.nlm.nih.gov/pubmed/32653009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12969-020-00450-9
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