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Quantitative Analysis of Antibody Survival across the Infant Digestive Tract Using Mass Spectrometry with Parallel Reaction Monitoring

Orally delivered antibodies may be useful for the prevention of enteric pathogen infection, but to be effective they need to survive intact across digestion through the gastrointestinal tract. As a test case, we fed a recombinant human antibody, palivizumab, spiked into human milk to four infants an...

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Detalhes bibliográficos
Publicado no:Foods
Main Authors: Kim, Bum Jin, Lueangsakulthai, Jiraporn, Sah, Baidya Nath P., Scottoline, Brian, Dallas, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353590/
https://ncbi.nlm.nih.gov/pubmed/32526824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/foods9060759
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