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Weak Interaction of the Antimetabolite Drug Methotrexate with a Cavitand Derivative

Formation of inclusion complexes involving a cavitand derivative (as host) and an antimetabolite drug, methotrexate (as guest) was investigated by photoluminescence measurements in dimethyl sulfoxide solvent. Molecular modeling performed in gas phase reflects that, due to the structural reasons, the...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Preisz, Zsolt, Nagymihály, Zoltán, Lemli, Beáta, Kollár, László, Kunsági-Máté, Sándor
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353011/
https://ncbi.nlm.nih.gov/pubmed/32570928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124345
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