Cancer Immunotherapeutic Potential of NKTT320, a Novel, Invariant, Natural Killer T Cell-Activating, Humanized Monoclonal Antibody

Invariant natural killer T cells (iNKTs) directly kill tumor cells and trans-activate the anti-tumor functions of dendritic cells (DC), natural killer (NK) cells, and T and B cells. As such, iNKTs serve as a powerful tool for use in cell-based cancer immunotherapy. iNKT cell activation commonly requ...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Patel, Nishant P., Guan, Peng, Bahal, Devika, Hashem, Tanwir, Scheuplein, Felix, Schaub, Robert, Nichols, Kim E., Das, Rupali
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352964/
https://ncbi.nlm.nih.gov/pubmed/32560408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124317
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