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Positive Feedback Loop of SNAIL-IL-6 Mediates Myofibroblastic Differentiation Activity in Precancerous Oral Submucous Fibrosis

Oral submucosal fibrosis (OSF) is a premalignant disorder of the oral cavity, and areca nut chewing is known to be a major etiological factor that could induce epithelial to mesenchymal transition (EMT) and activate buccal mucosal fibroblasts (BMFs). However, this detailed mechanism is not fully und...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Peng, Chih-Yu, Liao, Yi-Wen, Lu, Ming-Yi, Yang, Chieh-Mei, Hsieh, Pei-Ling, Yu, Cheng-Chia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352888/
https://ncbi.nlm.nih.gov/pubmed/32570756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12061611
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