S(+)-(2E)-N-(2-Hydroxypropyl)-3-Phenylprop-2-Enamide (KM-568): A Novel Cinnamamide Derivative with Anticonvulsant Activity in Animal Models of Seizures and Epilepsy

Epilepsy is one of the most frequent neurological disorders affecting about 1% of the world’s human population. Despite availability of multiple treatment options including antiseizure drugs, it is estimated that about 30% of seizures still remain resistant to pharmacotherapy. Searching for new anti...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Gunia-Krzyżak, Agnieszka, Żesławska, Ewa, Słoczyńska, Karolina, Żelaszczyk, Dorota, Sowa, Aleksandra, Koczurkiewicz-Adamczyk, Paulina, Popiół, Justyna, Nitek, Wojciech, Pękala, Elżbieta, Marona, Henryk
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352759/
https://ncbi.nlm.nih.gov/pubmed/32575479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124372
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