A Synthetic Cell-Penetrating Heparin-Binding Peptide Derived from BMP4 with Anti-Inflammatory and Chondrogenic Functions for the Treatment of Arthritis

We report dual therapeutic effects of a synthetic heparin-binding peptide (HBP) corresponding to residues 15–24 of the heparin binding site in BMP4 in a collagen-induced rheumatic arthritis model (CIA) for the first time. The cell penetrating capacity of HBP led to improved cartilage recovery and an...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Choi, Da Hyeon, Lee, Dongwoo, Jo, Beom Soo, Park, Kwang-Sook, Lee, Kyeong Eun, Choi, Ju Kwang, Park, Yoon Jeong, Lee, Jue-Yeon, Park, Yoon Shin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7352680/
https://ncbi.nlm.nih.gov/pubmed/32549254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21124251
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